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2 post-doc positions in Mechanobiology available in Milano

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Subjects

1. Mathematical modeling of therapeutic systems at the nano-scale

2.Mathematical modeling of morphogenesis in biological systems

Duration: 24 months (12+12), ideally starting on Jan./Feb. 2013

Place: MOX Laboratory, Politecnico di Milano, Italy

Project: the grant is an early initiative of the newly developing European Centre for Nanomedicine (CEN)

Description:

1. The post-doctoral position concerns the study of diffusion and transport properties of vascularized tissues for the development of new pharmacologic treatments in nano-medicine. The main scope is to build multi-scale models for biomedical applications, taking into account the mesoscopic phenomena of advection/diffusion, the transport mechanisms across the capillary network, and the receptor dynamics at the molecular scale. Particular attention will be given to the development of simulation tools for the design of nano-therapies in clinical oncology.
The ideal candidate has a PhD in applied mathematics, physics, mechanics or engineering, with a research experience in theoretical modeling of biological systems (continuum mechanics, hydrodynamics, transport theories) and a good practical knowledge of numerical tools, in particular finite elements. Basic notions of biology and medicine are requested in order favor the interactions with clinical partners for achieving experimental validations of the models.

2.  The post-doctoral position concerns the mathematical modeling of morphogenesis in biological systems, which is the emergence of a macroscopic shape thanks to the interactions of biochemical processes and/or out-of-equilibrium transport mechanisms at the micro-scale. The strategic objective is the development of mathematical theories and numerical tools for several applications in biosciences, from scaffold optimization in tissue engineering to the study of embryonic growth. Particular attention will be given to the development of new technologies for the fabrication of adaptive systems for capturing and releasing nano-particles.
The ideal candidate has a PhD in applied mathematics, physics, mechanics or engineering, with a solid background in biomechanical theories for biological systems (nonlinear elasticity, instability theories, multiscale-modeling) and documented skills in developing numerical tools (finite elements, level-set and/or immersed boundary methods). An interdisciplinary approach is requested for establishing fruitful collaborations with experimental research groups.

Applications should be submitted to
postdoc.cen@mate.polimi.it
Please include a CV, a motivation letter and the names of two possibile referees

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