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Postdoctoral position in Mechanical Engineering on Growth and Remodeling

vicky.nguyen's picture

Description:  Postdoc position in growth and remodeling in the Nguyen Lab, Department of Mechanical Engineering, The Johns Hopkins University


            Applications are invited for a postdoctoral candidate starting as soon as possible to study the role of collagen mechanochemistry in the growth and remodeling of soft connective tissues. Soft connective tissues exhibit a highly organized collagen structure that can remodel and grow in response to mechanical stimuli. Growth and remodeling can occur as part of physiological processes, such as aging and physical exertion. However, disordered or unchecked growth and remodeling is a defining feature of many diseases and disorders. Understanding how mechanical loading influence growth and remodeling of collagen structures is important for understanding the pathogenesis of diseases and for developing new therapeutic strategies that disrupts the mechanical pathways of pathological growth and remodeling.  The focus on collagen mechanochemistry is motivated by new and exciting molecular and fibril-scale experiments that show that mechanical loading can affect the rate of enzymatic degradation of collagen. The objective of the project is to develop constitutive models for the growth and remodeling of collagenous tissues that incorporate fibril-level microstructure, mechanisms of collagen degradation and deposition, and cellular interactions.  The project is collaborative and interdisciplinary, and the postdoctoral scholar will interact regularly with experimental collaborators at Northeastern University. Additional duties include communicating research findings in collaborative meetings, reports, journal publications, and conferences.  The postdoctoral scholar will also have opportunities to develop independent research ideas and write proposals as part of the postdoctoral training. 


The candidate is required to have a Ph.D. in Mechanical Engineering or Biomedical Engineering. Experience in biomechanics, constitutive modeling and finite element analysis is desired.


Prof. T. D. (Vicky) Nguyen

The Johns Hopkins University 


To apply, please e-mail a complete curriculum vitae, a representative publication, and the names and addresses of two references to the above contact. Please specifically put in the subject line: "Postdoc application for G&R". Review of applications will begin immediately and proceed until the position is filled.  Please note that in the event that I receive a lot of applications, I won't be able to reply to all applications or confirm that I have received them.  Thank you.


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