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Nicolas Cordero's picture

Max Planck Society: Independent Junior Research Group Leader positions

The Max Planck Society (MPS) aims at promoting young international scientists by enabling them to perform their research (in all fields pursued by the MPS) at a Max Planck Institute of their choice.

The MPS offers Independent Junior Research Group Leader positions (W2; equivalent to associate professor level without tenure) granted for a period of 5 years with the option for prolonging twice for 2 years. The deadline for application is January 10, 2007.

MechTube - applied mechanics outreach for children

Hello everyone,

Professor Suo suggested that I share this speculative idea that I once posted on Applied Mechanics News here on iMechanica!

In the future, we would like to reach out to children as early as their elementary school years to get them excited about topics drawn from Applied Mechanics. One approach to this goal takes inspiration from the successful "Le main a la pate", or "hands-in-dough", program in France ( ), but extends the idea of hands-on science to take advantage of the internet.

Some dates of iMechanica

  • 30 March 2007. At a suggestion of Henry Tan, an RSS feed for comments is added as a button"comment at a glance" on the right side of iMechanica.
  • 29 March 2007. An aggregator, "Random readings", is added to the rightside of iMechanica.
  • 7 March 2007. Michelle Oyen posted an entry "Making iMechanica a better global forum".

Intracellular CalciumWaves in Bone Cell Networks Under Single Cell Nanoindentation

In this study, bone cells were successfully cultured into a micropatterned network with dimensions close to that of in vivo osteocyte networks using microcontact printing and self-assembled monolyers (SAMs). The optimal geometric parameters for the formation of these networks were determined in terms of circle diameters and line widths. Bone cells patterned in these networks were also able to form gap junctions with each other, shown by immunofluorescent staining for the gap junction protein connexin 43, as well as the transfer of gap-junction permeable calcein-AM dye.

CFRAC 2007 International Conference on Computational Fracture and Failure of Materials and Structures

If you are interested by the computational aspects of fracture and failure of materials and structures,there is a dedicated conference for you : CFRAC 2007, which will be held in Nantes, France, 11-13 June 2007. It is an thematic conference of the European Community in Computational Methods in Applied Sciences (ECCOMAS). The for abstract is now closed. This conference wil involve a certian number

No need to worry about gravity at the atomic-/nano-scale

When a metal is grown onto a substrate of itself (homoepitaxy), the growth front is typically smooth, or at most is roughened by the formation of shallow hills (called surface mounds). The underlying reason for the roughening has been recognized to be of kinetic nature: Atoms landed on an upper terrace do not have enough time to overcome the "road blocks" provided by the steps and fill all the valleys (known as the Villian instability).

Molecular and Cellular Biomechanics Journal

A new journal dedicated to the field of Molecular and Cellular Biomechanics has been formed for about a year. Many members in this community (such as Ning Wang, Cheng Zhu, Phil LeDuc) are on the board of editors. You may want to check it out....

Zhigang Suo's picture

Some numbers of iMechanica

  • The number of registered users is 6037
  • The number of posts is 2896 (You can see the current number by clicking the newest post).
  • The number of comments is 6943 (You can see the current number by clicking the newest comment.)

Last updated on 19 March 2008

Related post: Some dates of iMechanica

MichelleLOyen's picture

ASME Summer Bioengineering Conference

Abstract submission is now open for the 2007 ASME Summer Bioengineering Conference, 20-24 June, 2007 in Keystone, Colorado. Full details can be found on the conference website. Please note that there is a vibrant and competitive student paper competition for different

The iMechanica Journal Club (iMech jClub)

Choose a channel featured in the header of iMechanica: 


2017 Themes and Discussion Leaders

Operating Notes for the iMechanica Journal Club

Choose a channel featured in the header of iMechanica: 

Guided by a thread that proposed the Journal Club, we evolve these operating notes. These notes are a work in progress, and will evolve as the iMechanica community and the Web technology evolve. Every moderator and architect can edit these notes. Every user can see the editing history. As always, every registered user can make suggestions by leaving comments.

Mass sensing by using a resonating microcantilever

We recently reported the mass sensing by using resonating microcantilevers. The characterization of mass-sensing and its related sensitivity was suggested on the basis of elasticity theory.

Model Reduction of Large Proteins for Normal Mode Studies

Recently, I reported the model reduction method for large proteins for understanding large protein dynamics based on low-frequency normal modes. This work was pubslihed at Journal of Computational Chemistry (click here).

Coarse-Graining of protein structures for the normal mode studies


Researcher Spotlight: Professor Lambert Ben Freund (LBF)

L. Ben FreundLambert Ben Freund (LBF) was born on November 23, 1942, in Johnsburg, Illinois, a tiny rural community of a few hundred people in the northeast corner of the state. This part of the Midwest was opened to European settlement by the Black Hawk War of the 1830s. A small delegation of his ancestors arrived in the area in 1841.

Quantum Stability of Metallic Thin Films and Nanostructures

When a metal system shrinks its dimension(s), the conduction electrons inside the metal feel the squeezing, and are forced into (discrete) quantum states. Such confined motion of the conduction electrons may influence the global or local stability of the low dimensional systems, and in the case of a thin film on a foreign substrate this "quantum energy" of electronic origin can easily overwhelm the strain effects in definging the film stability, thereby severely influencing the preferred growth mode (see, e.g., Suo and Zhang, Phys. Rev. B 58, 5116 (1998)).

Hanqing Jiang's picture

Controlled buckling of semiconductor nanoribbons for stretchable electronics

The success of electronic paper, roll-up displays, eye-like digital camera and many other potential applications of flexible and stretchable electronics will mainly depend on the availability of electronic materials to be stretched, compressed and bent. Previous efforts to develop electronic materials that can be mechanically deformed without breaking have mainly focused on small organic molecules and polymers. However, low charge mobility of these organic materials cannot compete with devices made from inorganic materials such as silicon and gallium arsenide.

Ashkan Vaziri's picture

Mechanics and deformation of the nucleus in micropipette aspiration experiment

Robust biomechanical models are essential for studying the nuclear mechanics and can help shed light on the underlying mechanisms of stress transition in nuclear elements. Here, we develop a computational model for an isolated nucleus undergoing micropipette aspiration. Our model includes distinct components representing the nucleoplasm and the nuclear envelope. The nuclear envelope itself comprises three layers: inner and outer nuclear membranes and one thicker layer representing the nuclear lamina.

Atomistic simulations for the evolution of a U-shaped dislocation in fcc Al

We show, through MD simulations, a new evolution pattern of the U-shaped dislocation in fcc Al that would enrich the FR mechanism. Direct atomistic investigation indicates that a U-shaped dislocation may behave in different manners when it emits the first dislocation loop by bowing out of an extended dislocation. One manner is that the glissile dislocation segment always bows in the original glide plane, as the conventional FR mechanism. Another is that non-coplanar composite dislocations appear owing to conservative motion of polar dislocation segments, and then bow out along each slip plane, creating a closed helical loop. The motion of these segments involves a cross-slip mechanism by which a dislocation with screw component moves from one slip plane into another. Ultimately, such non-coplanar evolution results in the formation of a FR source.


I am writing to you to bring to your attention a new Master Course on Computational Mechanics, which has been awarded the Erasmus Mundus label.

It is an international Master course given jointly in English by the Universidad Politécnica de Cataluña (Barcelona), University of Wales Swansea), Ecole Centrale Nantes and Universität Stuttgart with the collaboration of CIMNE International Centre for Numerical Methods in Engineering, Barcelona). The Erasmus Mundus program:

Alexander A. Spector's picture

Back to the Mechanics vs. Biochemistry in Cellular Mechanotransduction

In his interesting response to our comment posted on 11/28, Ning Wang focused on the transmission of a local force generated at the adhesion site(s). We agree that this is a question important to our understanding of the signaling to the nucleus. The question is not only about the range of the force transmission but also about the magnitude of such force because the nucleus is several times stiffer than the cytoskeleton.

A Model for Superplasticity not Controlled By Grain Boundary Sliding

It is commonly assumed that grain boundary sliding can control plastic deformation in fine grained crystalline solids.  Superplasticity is often considered to be controlled by grain boundary sliding, for example.  I have never accepted that view, though my own opinion is very much at odds with the commonly accepted picture.  When I was asked to write a paper in honor of Professor F.R.N. Nabarro's 90th birthday (Prof.

A structure-based sliding-rebinding mechanism for catch bonds

This is a paper by Jizhong Lou and myself, which is in press in Biophysical Journal.

Abstract.  Catch bonds, whose lifetimes are prolonged by force, have been observed in selectin-ligand interactions and other systems. Several biophysical models have been proposed to explain this counter-intuitive phenomenon, but none was based on the structure of the interacting molecules and the noncovalent interactions at the binding interface. Here we used molecular dynamics simulations to study changes in structure and atomic-level interactions during forced unbinding of P-selectin from P-selectin glycoprotein ligand-1. A mechanistic model for catch bonds was developed based on these observations. In the model, "catch" results from forced opening of an interdomain hinge that tilts the binding interface to allow two sides of the contact to slide against each other. Sliding promotes formation of new interactions and even rebinding to the original state, thereby slowing dissociation and prolonging bond lifetimes. Properties of this sliding-rebinding mechanism were explored using a pseudo-atom representation and Monte Carlo simulations. The model has been supported by its ability to fit experimental data and can be related to previously proposed two-pathway models.

How can we obtain more information from protein structure?

We know - or believe - protein function is determined by structure. Crystallographic and NMR studies can provide protein structures with atomic-level details at equilibrium. MD simulations can follow protein conformational changes in time with fs temporal resolution in the absence or presence of a bias mechanism, e.g., applied force, used to induce such changes.


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