The modeling and performance of mechanical resonators used for mass detection of bio-cells, nanocrystalline materials characterization, and disease diagnosis of human immune-viruses (HIVs) are investigated. To simulate the real behavior of these mechanical resonators, a novel distributed-parameter model based on Euler-Bernoulli beam theory is developed. This model is equipped with a micromechanical model and an atomic lattice model to capture the inhomogeneity nature of the material microstructure.
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