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cell mechanics

ruogang zhao's picture

Postdoctoral position in mechanobiology, Buffalo, New York

One postdoctoral position will be available in Fall, 2015 in the Department of Biomedical Engineering at the State University of New York at Buffalo (SUNY). The research area will focus on using bio-MEMS techniques to create novel cell culture platforms for cell mechanics and mechanobiological studies. Projects may involve studies of the fibrosis diseases, cancer invasion and stem cell differentiation. Some research topics can be found on our website at http://www.acsu.buffalo.edu/~rgzhao/index.html

azadpoor's picture

Call for abstracts and special issue papers: Computational mechanics of cells, tissues, and biomaterials

We would be pleased to have a contribution from you or from one of the members of your group among the presentations of the symposium entitled
COMPUTATIONAL MECHANICS OF CELLS TISSUES  AND BIOMATERIALS
organized within the joint World Congress on Computational Mechanics and European Conference on Computational Mechanics (http://www.wccm-eccm-ecfd2014.org/frontal/default.asp )
to be held on 20-25 July 2014 in Barcelona (Spain).

Living cells behave as fluid-filled sponges

Animal cells behave like fluid-filled sponges in response to being mechanically deformed according to new research published in Nature Materials.

Scientists from the London Centre for Nanotechnology at UCL have shown that animal cells behave according to the theory of ‘poroelasticity’ when mechanically stimulated in a way similar to that experienced in organs within the body. The results indicate that the rate of cell deformation in response to mechanical stress is limited by how quickly water can redistribute within the cell interior.

Konstantin Volokh's picture

On Tensegrity in Cell Mechanics

All models are wrong, but some are useful. This famous saying mirrors the situation in cell mechanics as well. It looks like no particular model of the cell deformability can be unconditionally preferred over others and different models reveal different aspects of the mechanical behavior of living cells. The purpose of the present work is to discuss the so-called tensegrity models of the cell cytoskeleton. It seems that the role of the cytoskeleton in the overall mechanical response of the cell was not appreciated until Donald Ingber put a strong emphasis on it.

Tian Zhi Luo's picture

2011 International Dictyostelium Conference, August 14-18, Baltimore, MD USA

The annual International Dictyostelium Conference will be held in Baltimore, MD USA from August 14 to 18. Dictyostelium has been extensively used as a model organism for the study of cell mechanics, motility, chemotaxis, cell division and other biological events that involve cell shape change and the mechanical behaviors of cells. In this coming meeting, there will be 70 oral presentations and 100 posters covering above topics.

http://dicty11.dictybase.org

 

Simple Cell Traction Force Script for Elastic Micropatterned Substrata

Hi readers, 

 This is MATLAB code that was written by myself and collaborators that we've sought to make available to the wider research community. The program is intended to track the displacements of micropatterned dots on a substrate in a similar manner to that performed by  Maloney et al. in "Influence of Finite Thickness on cellular adhesion-induced deformation of an compliant substrata". Physical Review E. 2008.

Chris W Smith's picture

Chair in Cell Mechanics

Chair in Cell Mechanics, University of Exeter

The University of Exeter
is significantly expanding its capacity in Science and Engineering, with 275 million
GBP (approx 440M USD) capital spend on campus and 80M GBP (130M USD) on new academic staff.

Chris W Smith's picture

New Chairs at University of Exeter

The University of Exeter will shortly announce several new chairs it is seeking to fill.

The chairs are full tenured chairs and in the following areas -

Cell Mechanics (two chairs, one nominally experimental and one nominally theoretical).

Structural Dynamics, possibly with an aerospace flavour.

If you are interested, or know someone who might be, please contact me (c.w.smith-at-exeter.ac.uk) for an informal discussion.

Regards,

Chris Smith

 

Postdoc in Physical Chemistry for Cell Mechanics at University of Mons

A postdoctoral position is available for a highly
motivated candidate to study the physical principles of cell motility in the
Biophysics Group of the Interfaces & Complex Fluids Lab at the University
of Mons in collaboration with the Bio- and Soft Matter Group of the Institute
of Condensed Matter and Nanosciences at the Université catholique de Louvain.

Tian Zhi Luo's picture

A new book chapter of the role of the actin cytoskeleton in mechanosensation

We wrote a book chapter about the role of the actin cytoskeleton in mechanosensation. The book title is Mechanosensitivity and Mechanotransduction, edited by A, Kamkin and I. Kiseleva and published by Springer-Verlag, New York.". 

In this chapter, we try to integrate mechanics, materials science, biophysics and biology together to give a most updated view of this field. We also want to introduce the feedback loop concept to mechanicians who are interested in studying biological systems.

I attached the pdf version and the follwoing is the subtitles of the chapter. 

Fluid-structure Interaction in Cell Mechanics

We present an application of fluid-structure interaction analysis to the mechanics of red blood cells. For more information see the following link:

http://www.adina.com/newsgH60.shtml

Please recall that we offer a special academic package, for research and teaching, for university users. For more information see:

http://www.adina.com/educ.shtml

Teng Li's picture

Mechanics of microtubule buckling in living cells

As the most rigid cytoskeletal filaments, microtubules bear compressive forces in living cells, balancing the tensile forces within the cytoskeleton to maintain the cell shape. It is often observed that, in living cells, microtubules under compression severely buckle into short wavelengths. By contrast, when compressed, isolated microtubules in vitro buckle into single long-wavelength arcs. The critical buckling force of the microtubules in vitro is two orders of magnitude lower than that of the microtubules in living cells.

Tian Zhi Luo's picture

MD simulation of the cell shape change during cytokinesis

The simulation was conducted under constant force condition. Initially, the cell had a spherical shape. After being deformed by the virtual forces that were applied on the molecules on the middle great circle, the cell underwent continuous shape changes. The virtual forces were originated from the myosin motion along the actin filaments in the contractile ring.

Taxonomy upgrade extras: 
Tian Zhi Luo's picture

coarse grained MD simulation of cell division associated with the z-ring structure

The simulation code is written according the article published by J. Li et al. in Biophysics Journal 2005. The force associated with the z-ring is applied in the middle of a cylindrical cell. Continuum solution of the cell division can be found in the paper published by G. Lan et al. in PNAS 2006.

Taxonomy upgrade extras: 

Entropic-elasticity-controlled dissociation and energetic-elasticity-controlled rupture induce catch to slip bonds in cell-adhes

In order to achieve a wide variety of biological phenomena, the abilities of cells to contact effectively and interact specifically with neighboring media play a central role. It is known that cells can sense the chemical and mechanical properties of surrounding systems and regulate their adhesion and movement through binding protein molecules within cell membrane. The kinetics of binding molecules interacting with ligands is of great interest in biophysical society. There are lots of discussions and contributions on cell mechanics from our mechanical society, e.g.

Recruiting PhD students for Cell Mechanics Lab at Rensselaer

Full support is available for 2 PhD students in cellular mechanics group in Biomedical Engineering Department at Rensselaer Polytechnic Institute.  

The applicants should have mechanics, materials or soft matter physics background, with some experimental experience at micro-scales.  Experience with any of the following is considered a
plus: computational mechanics, cell/tissue culture, microscopy, image analysis, photonics.

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