Nature recently favorably reviewed a new self-published book, based on a blog , by a "female physical sciences professor" in the US. While the overarching theme is clearly about being a female in a male-dominated world, the writings on the blog (and in the book) are in many places general and provide lots of good advice and anecdotes about acadmic life. The book is available as a download on Lulu and is highly recommended reading, not to mention an interesting web-2.0 phenomenon.
Starting from January 2006, my group has been posting in Modeling Place as a blogspot to share research experience and ideas. We will gradually migrate to iMechanica for better publicity and more web functions.