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Shuolun Wang's blog

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Multi-physics modeling and finite element formulation of corneal UV cross-linking

The UV cross-linking technique applied to the cornea is a popular and effective therapy for eye diseases such as keratoconus and ectatic disorders. The treatment strengthens the cornea by forming new cross-links via photochemical reactions and, in turn, prevents the disease from further developing.

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Numerical investigation of biomechanically coupled growth in cortical folding

Cortical folding—the process of forming the characteristic gyri (hills) and sulci (valleys) of the cortex—is a highly dynamic process that results from the interaction between gene expression, cellular mechanisms, and mechanical forces. Like many other cells, neurons are sensitive to their mechanical environment. Because of this, cortical growth may not happen uniformly throughout gyri and sulci after the onset of cortical folding, which is accompanied by patterns of tension and compression in the surrounding tissue.

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