iMechanica - collagen fibrils
https://imechanica.org/taxonomy/term/1908
enMulti-functionality of collagen fibrils may provide nanomechanical heterogeneity in bone in addition to clues to the Wolff’s law
https://imechanica.org/node/6917
<div class="field field-name-taxonomy-vocabulary-6 field-type-taxonomy-term-reference field-label-hidden"><div class="field-items"><div class="field-item even"><a href="/taxonomy/term/76">research</a></div></div></div><div class="field field-name-taxonomy-vocabulary-8 field-type-taxonomy-term-reference field-label-hidden"><div class="field-items"><div class="field-item even"><a href="/taxonomy/term/315">bone</a></div><div class="field-item odd"><a href="/taxonomy/term/474">piezoelectricity</a></div><div class="field-item even"><a href="/taxonomy/term/1908">collagen fibrils</a></div><div class="field-item odd"><a href="/taxonomy/term/4441">Nanomechanical Heterogeneity</a></div></div></div><div class="field field-name-body field-type-text-with-summary field-label-hidden"><div class="field-items"><div class="field-item even"><p class="MsoNormal">
Single collagen fibrils, with as small as 50 nm in diameter, are the main organic component of bone. They are the most abundant proteins in mammals with multifunctional tasks in tissues with different mechanical requirement such as bone, tendon, cornea, and skin. In a series of experimental studies at the nanoscale on individual collagen fibrils, we show that the characteristic banding pattern of ~67 nm in axial direction of a single collagen fibril, i.e. the gap and overlap regions, is the main cause of multifunctionality of collagen fibrils. They provide the smallest scale of nanomechanical heterogeneity in related tissues. In addition, they give the collagen fibril its unique piezoelectric behavior that may provide basis for the Wolff’s law on bone growth and remodeling.
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<span><span>1.<span> </span></span></span><em>Biomacromolecules</em>, <strong>2009</strong>, <em>10</em> (9), pp 2565–2570
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<a href="http://pubs.acs.org/doi/abs/10.1021/bm900519v"><span>http://pubs.acs.org/doi/abs/10.1021/bm900519v</span></a>
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<span><span>2.<span> </span></span></span><em>ACS Nano</em>, <strong>2009</strong>, <em>3</em> (7), pp 1859–1863
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<a href="http://pubs.acs.org/doi/abs/10.1021/nn900472n"><span>http://pubs.acs.org/doi/abs/10.1021/nn900472n</span></a>
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<span><span>3.<span> </span></span></span>Nanotechnology <strong>20</strong> 085706 (6pp)
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<a href="http://www.iop.org/EJ/abstract/0957-4484/20/8/085706">http://www.iop.org/EJ/abstract/0957-4484/20/8/085706</a>
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</div></div></div>Sat, 10 Oct 2009 16:21:20 +0000Majid Minary6917 at https://imechanica.orghttps://imechanica.org/node/6917#commentshttps://imechanica.org/crss/node/6917Tension Testing of Individual Collagen Fibrils
https://imechanica.org/node/2742
<div class="field field-name-taxonomy-vocabulary-6 field-type-taxonomy-term-reference field-label-hidden"><div class="field-items"><div class="field-item even"><a href="/taxonomy/term/76">research</a></div></div></div><div class="field field-name-taxonomy-vocabulary-8 field-type-taxonomy-term-reference field-label-hidden"><div class="field-items"><div class="field-item even"><a href="/taxonomy/term/1908">collagen fibrils</a></div></div></div><div class="field field-name-body field-type-text-with-summary field-label-hidden"><div class="field-items"><div class="field-item even"><p>In a <a href="/node/2653">recent discussion</a> it was suggested that it would be useful to perform tension tests on collagen fibrils. We have developed a MEMS-based experimental procedure that is capable of applying very large strains to individual collagen fibrils. The attached paper presents illustrative data; an upcoming paper will present much more data that illustrates the rich behavior of these fibrils during loading and unloading tests.</p>
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<tr class="odd"><td><span class="file"><img class="file-icon" alt="PDF icon" title="application/pdf" src="/modules/file/icons/application-pdf.png" /> <a href="https://imechanica.org/files/royal%20society%20collagen%20fibrils_0.pdf" type="application/pdf; length=899324" title="royal society collagen fibrils.pdf">royal society collagen fibrils.pdf</a></span></td><td>878.25 KB</td> </tr>
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</div></div></div>Fri, 22 Feb 2008 17:52:42 +0000Roberto Ballarini2742 at https://imechanica.orghttps://imechanica.org/node/2742#commentshttps://imechanica.org/crss/node/2742Error | iMechanica