We made a simple model for understanding the dynamic behavior of nanomechanical resonator in response to biomolecular interactions. Specifically, in our model, we considered the nanomechanical resonator, on whose surface the biomolecules (dsDNA) are adsorbed, such that Hamiltonian of the system consists of elastic bending energy of nanomechanical resonator and potential energy for biomolecular interaction (i.e. DNA-DNA interaction). It was shown that DNA-DNA interaction plays a role on the resonant frequency shift for nano-scale resonators. This work was accepted for publications at Physical Review B.

Dynamical Response of Nanomechanical Resonators to Biomolecular Interactions