In the developing embryo, tissues differentiate, deform, and move in an
orchestrated manner to generate various biological shapes driven by the complex
interplay between genetic, epigenetic, and environmental factors. Mechanics
plays a key role in regulating and controlling morphogenesis, and quantitative
models help us understand how various mechanical forces combine to shape the
embryo. Models allow for the quantitative, unbiased testing of physical
mechanisms, and when used appropriately, can motivate new
experimentaldirections. This knowledge benefits biomedical researchers who aim
to prevent and treat congenital malformations, as well as engineers working to
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