Megan McCain's blog

In the ventricle of the heart, the cells (myocytes) are not isotropically arranged. Myocytes are cylindrically shaped and align edge to edge, and then form a large sheet of parallel rows of aligned cells. This "sheet" is wrapped around itself to form the thick wall of the heart. Myocytes are mechanically coupled to each other by desmosomes, and are electrically coupled to each other by connexins. These connections are extremely important in assuring the heart beats synchronously.

Although I know it is not very original, I am recommending Timoshenko's Theory of Elasticity textbook. I find this book useful because it solves many classical solid mechanics problems without assuming the reader has a strong background in the subject (like me). When I am having difficulty with a homework problem, I turn to the index and it usually directs me to a section of the book directly related to the problem, or sometimes even the solution itself. Many parts of the book complement the course, such as the chapters "Plane Stress and Plane Strain" and "Analysis of Stress and Strain in 3 Dimensions."

The book starts with basic definitions and derivations of stress and strain, then applies these equations to solve problems in different coordinate systems. It also includes chapters on more specific topics, like torsion and thermal stress.

I am a first year grad student in bioengineering working in Dr. Parker's Disesase Biophysics Group (http://www.deas.harvard.edu/diseasebiophysics/). I attended Washington University in St. Louis for undergrad, where I double majored in biomedical engineering and biology and minored in chemistry. The only courses I have taken related to solid mechanics are Biomechanics and Transport Phenomena, both of which covered basic mechanics. As an undergrad, I worked in a research lab that focused on cardiac electrophysiology. The lab I am in now is interested in how the mechanical and electrical behaviors of cardiac cells are related, so I need to gain a stronger background in mechanics to match my background in electrophysiology. I hope that this class will help me develop an intuition about the mechanical behavior of objects, which I can apply to the mechanics of cellular events.