After almost seven years development, we have achieved more and more clarity with the concept of structure gene and it governing principles (mechanics of structure genome). My recent talk on MSG summarizes its relations with materials genome, common structural theories, micromechanics, multiscale modeling, as well as its current application to deployable structures, homogeneous 3D elements, machine learning assisted multiscale modeling. You can watch this talk at Youtube https://www.youtube.com/watch?v=7d5LuQrLpCM&t=5s. If you cannot access Youtube, you can watch it on cdmHUB at https://cdmhub.org/resources/1940/video?resid=1941&time=00:00:01.