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Cell-adhesion

The maximum receptor-ligand bond spacing to ensure cell adhesion in ligand-coated substrates

Recent experiments by Arnold et al. (ChemPhysChem, vol. 5, 2004, p383 ) revealed that a distance of less than 58-73 nm between receptor-ligand bonds is necessary to ensure focal adhesion in cells adhering to ligand-coated substrate. An elegant solution to this problem is supplied by Lin, Inamdar, and Freund.

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