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Enquiry about modelling a cylinder filled with water in ABAQUS / CFD

Dear All

 My name is Paula , I am new user in CFD coupled with ABAQUS. I would like to know and understand how can I simulate cell wall filled with  of water. If the tank sloshing example good way to start with cfd/ABAQUS? .

The problem
is that the cytoplasm ( high % is water) has an internal pressure.
would like to make the simulation with outside presure ( hydrostatic pressure)
and find which is the outside pressure to brake the cell
wall and the cytoplasm gets free.

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