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Rac activation by stress does not depend on Src

Submitted by Ning Wang on

It is known that platelet derived growth factor (PDGF) induced Rac activation depends on Src activity. However, we find that a local stress of physiologic magnitude via integrins can directly activate Rac GTPase rapidly, independent of the Src activity. Our finding on the stress-induced rapid Rac activation challenges the conventional wisdom on mechanotransduction and suggests that stress-induced signaling via focal adhesions does not follow signal transduction pathways induced by growth factors. To view the whole paper:

Two post-doctoral researcher positions in computational materials sciences available at Academia Sinica in Taiwan

Submitted by barbarossapao on

Two post-doctoral researcher positions focusing on the two topics listed below are available immediately at Research Center for Applied Sciencs at Academia Sinica (中央研究院) in Taipei, Taiwan.

1) Ab initio MD simulations of Li ion diffusion on / inside novel electrode materials using accelerated MD. Candidates with expertises in ab initio MD, in particular, BOMD,  are highly desirable.

Thermo-mechanical Modeling of Friction Welding

Submitted by ADINA Support on

We present an application of ADINA in the thermo-mechanical analysis of friction welding. Please see: 



http://www.adina.com/newsgH61.shtml



You can find many other examples of applications of ADINA in the analysis of multiphysics problems here:   



http://www.adina.com/multiphysics.shtml

Civil Engineering Conference in the Asian Region and Australasian Structural Engineering Conference 2010

Submitted by Sakdirat Kaewunruen on

Civil Engineering Conference in the Asian Region and Australasian Structural Engineering Conference 2010

The 5th International Civil Engineering Conference (CECAR5) hosted by Engineers Australia, together with the Australasian Structural Engineering Conference (ASEC 2010) will bring together a broad cross-section of the civil and structural engineering professions who want to learn, network and advance their technical skills.

modelling of composite sheet in ansys and how to apply tsai wu failure criteria.,.

Submitted by mechevikas on

hello.
any idea how to design fiber glass reinforced plastic(composite sheet) in ansys and how to apply tsai wu failure criteria.,.,plz tell me i am not able to that.,.,or it is easy to make in abaqus...is any option we get in ansys about composites or failure criteria...please give some comments if u know some thing.

Two-point Tensors

Submitted by Mubeen on

I am confused about the use of two-point tensors in elasticity. The deformation tensor F and first PK tensor are two point tensors, and the "two-point" property arises from use of two different Coordinate System When a continuum body is deformed, why it is necessary to move the Coordinate System as well? (or alternatively, why the coordinate system is attached to the body itself??, isn't it possible to use a general coordinate system which can represent the deformations and also account for the rigid body rotations of the continuum body?).