Domain decomposition-based structural condensation of large protein structures for understanding their conformational dynamics
Abstract
Bacterial outer membrane porins (Omp) that have robust ß-barrel structures, show potential ap-
plications for nanomedicine devices in synthetic membranes and single molecule detection biosensors.
Here, we explore the conformational dynamics of a set of 22 outer membrane porins, classified into
five major groups: general porins, specific porins, transport Omps, poreless Omps and composed
pores. Normal mode analysis, based on mechanical vibration theory and elastic network model, is
This paper has been accepted for publication in Soft Matter. DOI: 10.1039/c0sm00335b.
What is stress? Who has ever seen stress? Is stress a physical quantity?
Professor Yi-Heng Chen, Xi’an Jiaotong University, 710049, P.R.China
e-mail: yhchen2 [at] mail.xjtu.edu.cn (yhchen2[at]mail[dot]xjtu[dot]edu[dot]cn)
In fact, this question has been bothering the present author for more than 15 years.
W.M. Keck Institute for Space Studies Postdoctoral Fellowships Announcement of Opportunity
Application Deadline: 5pm PST 24 November 2010
The Department of Industrial Engineering at the University of Pittsburgh anticipates an opening for a postdoctoral associate starting September 2010. The position’s primary area of research will focus on mechanics of the microforming processes and characterizing the thermomechanics of deformation at micrometer length-scales.
Constitutive relations, 2-D vs. 3-D. The starting point for modeling cellular membranes is the constitutive relations in 2-D space. It is important to set up the corresponding equations directly in two dimensions rather than to consider them as an asymptotic limit of three-dimensional relationships, like it is done in the shell theory. The main reason for the direct 2-D relations is that 3-D continuum approaches are not applicable to membranes whose thickness in on the order of magnitude of the dimension of a single molecule.
NIH-FUNDED POSTDOCTORAL FELLOWSHIP IN FINTIE ELEMENT MODELING OF OCULAR TISSUES - TWO YEAR TERM
A postdoctoral associate position at MIT is available immediately,
focused on the analysis and development of multifunctional thermal
management structures, by using theoretical and atomistic multiscale
modeling and simulation. This project specifically involves calculations
of thermal and mechanical properties of graphene based metal- and
polymer nanocomposites, with a focus on various aspects such as
interfacial transport properties, tunability, mutability and phonon
engineering. Additional aspects of the project relate to the general
Physical gels are characterized by dynamic cross-linksthat are constantly created and broken, changing its state between solid andliquid under influence of environmental factors.