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A unique feature of mechanotransduction is revealed

Submitted by Ning Wang on

It is generally believed that similar to soluble ligand-induced signal transduction, mechanotransduction initiates at the local force-membrane interface (e.g., at focal adhesions) by inducing local conformational changes or unfolding of membrane-bound proteins, followed by a cascade of diffusion-based or translocation-based signaling in the cytoplasm. However, all published reports, including past studies with the reporter type of construct extended here, were limited in timescale to address this fundamental issue.

Review paper by Professor Jerry Ericksen on Cauchy-Born rule; Special issue on scale effects---freely available for a month

Submitted by Pradeep Sharma on

Xin-Lin Gao and I had the pleasure of guest-editing a special  issue on "scale effects in mechanics" for the journal, Mathematics and Mechanics of Solids (editor: Professor David Steigmann , UC Berkeley).

Postdoctoral position in Multiscale Modeling

Submitted by marisolkoslowski on

The Computational Solid Mechanics group under the direction of Prof. Marisol Koslowski in the School of Mechanical Engineering at Purdue has an opening for a postdoctoral position in the area of multiscale modeling as part of the project “Plasticity in ultrafine grained materials” funded by DOE. A successful candidate is expected to have a strong background in computational solid mechanics and programming experience. While experience in plasticity using dislocation dynamics or phase field methods is a plus, all outstanding candidates will be considered.

Coupling meshfree and Finite element methods

Submitted by Rajathachal.MK on

I just wanted to know if i can consider one part of a FE model as a meshless part and form the global stiffness matrix just by assembling the meshfree stiffness matrix corresponding to the meshfree zone and the FE stiffness matrix of the rest. And then apply the boundary conditions to the model and solve. I would use RKPM to generate the meshfree stiffness matrix.